Bioinformatics Seminar
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Advancing protein sequence analysis with protein language models Wednesday, December 10, 2025 - 11:30am to 1:00pm Protein language models (PLMs) have emerged as transformative tools for understanding and interpreting protein sequences, enabling advances in structure prediction, functional annotation, and variant effect assessment directly from sequence alone. |
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Towards virtual cells - the need for actionable, robust perturbation models Wednesday, December 3, 2025 - 11:30am to 1:00pm Computational cell biology is evolving from descriptive atlases to predictive, actionable models — from mapping what cells are to simulating what they do. |
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AI for Genomes: Rethinking de novo Assembly Wednesday, November 19, 2025 - 11:30am to 1:00pm Accurately resolving genomic paths in assembly graphs is a key challenge in de novo genome assembly, especially in the presence of repeats that create tangles and fragmentation. |
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From Networks to Subtypes: Statistical Frameworks for Mechanistic Insights into Complex Disease Genetics Wednesday, November 12, 2025 - 11:30am to 1:00pm Complex diseases often arise from diverse genetic mechanisms acting through interconnected pathways and frequently encompass multiple hidden subtypes that share similar diagnostic features but have distinct genetic origins. |
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Exploring 100 million years of mammalian evolution for the origins of exceptional traits Wednesday, October 29, 2025 - 11:30am to 1:00pm The Zoonomia Project, one of the largest comparative genomics initiatives ever undertaken, compared 240 mammalian species spanning over 100 million years of evolutionary history. |
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Creating the next generation of genome analysis tools with deep learning Wednesday, October 22, 2025 - 11:30am to 1:00pm Deep learning is fueling a revolution in genomics, enabling the development of a new generation of analysis tools that offer unprecedented accuracy. |
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From Data to Knowledge: Integrating Clinical and Molecular Data for Predictive Medicine Wednesday, October 15, 2025 - 11:30am to 1:00pm Alzheimer’s disease (AD) remains one of the most pressing medical challenges, with limited therapeutic options and heterogeneous disease trajectories complicating diagnosis and treatment. |
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AI integrating imaging and genetics to understand human evolution, development, aging, and disease Wednesday, October 8, 2025 - 11:30am to 1:00pm Imaging has been the primary means of diagnosing as well as tracking the progression of many diseases for decades but has largely been collected in isolation. |
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Furthering our understanding of human genetic variation: the human pangenome reference project second release Wednesday, October 1, 2025 - 11:30am to 1:00pm Human genomics has relied on a single reference genome for the last twenty years. |
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Discovering New Biochemistry from Biological Conflicts Wednesday, September 24, 2025 - 11:30am to 1:00pm Biological replicators are locked in deeply intertwined genetic conflicts with each other. |
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